Nilotinib is a medication used to treat chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). It works by blocking the activity of a protein called BCR-ABL, which is produced by the abnormal gene that causes CML and Ph+ ALL.

The recommended dose of nilotinib may vary depending on specific factors, such as the stage of the disease and other individual factors like age and overall health. It is usually taken by mouth, with or without food, once or twice daily.

Like all medications, nilotinib can cause some side effects. Common side effects may include nausea, diarrhea, fatigue, headache, and fluid retention. More serious side effects can include QT prolongation (a heart rhythm problem), liver toxicity, and low blood counts. It is important to talk to your healthcare provider about any concerns or symptoms you are experiencing while taking this medication.